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CDC25C Antibody (ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - CDC25C Antibody (ascites) AM1908a
    Western blot analysis of CDC25C (arrow) using CDC25C (Cat. #AM1908a). 293 cell lysates (2 μg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CDC25C gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30307
Other Accession NP_001781.2, NP_073720.1
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names 233CT9.6.6
Calculated MW 53365 Da
Additional Information
Gene ID 995
Other Names M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C
Target/Specificity This CDC25C monoclonal antibody is generated from mouse immunized with CDC25C recombinant protein.
Dilution WB~~1:1000~8000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDC25C Antibody (ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC25C
Function Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
Cellular Location Nucleus
Research Areas
Citations (0)

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This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq].


Moon, D.O., et al. Oncol. Rep. 24(1):271-276(2010) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010) Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press : Franckhauser, C., et al. PLoS ONE 5 (7), E11798 (2010) : Wang, Z., et al. BMC Cancer 10, 233 (2010) :

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$ 295.00
Cat# AM1908a
(40 western blots)
Availability: In Stock
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