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CSNK2B Antibody

Mouse Monoclonal Antibody (Mab)

     
  • WB - CSNK2B Antibody AM1923b
    CSNK2B Antibody (Cat. #AM1923b) western blot analysis in K562 cell line lysates (35μg/lane).This demonstrates the CSNK2B antibody detected the CSNK2B protein (arrow).
    detail
  • WB - CSNK2B Antibody AM1923b
    CSNK2B Antibody (Cat. #AM1923b) western blot analysis in mouse NIH-3T3 cell line lysates (35μg/lane).This demonstrates the CSNK2B antibody detected the CSNK2B protein (arrow).
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P67870
Other Accession P67874, P67873, P67872, P67871, P67869, P67868, NP_001311.3
Reactivity Human, Mouse
Predicted Bovine, Chicken, Pig, Rabbit, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone/Animal Names 260CT10.1.1
Calculated MW 24942 Da
Additional Information
Gene ID 1460
Other Names Casein kinase II subunit beta, CK II beta, Phosvitin, Protein G5a, CSNK2B, CK2N, G5A
Target/Specificity This CSNK2B monoclonal antibody is generated from mouse immunized with CSNK2B recombinant protein.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCSNK2B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSNK2B (HGNC:2460)
Synonyms CK2N, G5A
Function Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (PubMed:11239457, PubMed:16818610). Participates in Wnt signaling (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.

References

Shehata, M., et al. Blood 116(14):2513-2521(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Olsen, B.B., et al. Int. J. Oncol. 36(5):1175-1182(2010)
Shi, Y., et al. BMB Rep 42(12):840-845(2009)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 182.50
$ 70.00
Cat# AM1923b
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