|Application ||WB, E|
|Other Accession||P67874, P67873, P67872, P67871, P67869, P67868, NP_001311.3|
|Predicted||Rat, Rabbit, Pig, Chicken, Bovine|
|Calculated MW||24942 Da|
|Other Names||Casein kinase II subunit beta, CK II beta, Phosvitin, Protein G5a, CSNK2B, CK2N, G5A|
|Target/Specificity||This CSNK2B monoclonal antibody is generated from mouse immunized with CSNK2B recombinant protein.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CSNK2B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
Shehata, M., et al. Blood 116(14):2513-2521(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Olsen, B.B., et al. Int. J. Oncol. 36(5):1175-1182(2010)
Shi, Y., et al. BMB Rep 42(12):840-845(2009)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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