|Application ||WB, E|
|Calculated MW||53536 Da|
|Other Names||Desmin, DES|
|Target/Specificity||This DESM monoclonal antibody is generated from mouse immunized with DESM recombinant protein.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DESM Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.|
|Cellular Location||Cytoplasm. Cell membrane, sarcolemma|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq].
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
van Spaendonck-Zwarts, K., et al. Clin. Genet. (2010) In press :
Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)
Bar, H., et al. J. Mol. Biol. 397(5):1188-1198(2010)
Levin, J., et al. J. Neuropathol. Exp. Neurol. 69(4):415-424(2010)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.