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GSN Antibody (N-term) (ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - GSN Antibody (N-term) (ascites) AM1936a
    GSN Antibody (N-term) (Cat. #AM1936a) western blot analysis in MDA-MB435 cell line lysates (35μg/lane).This demonstrates the GSN antibody detected the GSN protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P06396
Other Accession Q3SX14, NP_000168.1
Reactivity Human
Predicted Bovine
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 328CT2.2.1
Calculated MW 85698 Da
Antigen Region 230-259 aa
Additional Information
Gene ID 2934
Other Names Gelsolin, AGEL, Actin-depolymerizing factor, ADF, Brevin, GSN
Target/Specificity This GSN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the N-terminal region of human GSN.
Dilution WB~~1:100~4000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGSN Antibody (N-term) (ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSN
Function Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
Cellular Location Isoform 2: Cytoplasm, cytoskeleton.
Tissue Location Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells
Research Areas
Citations (0)

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The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.


Pottiez, G., et al. Rapid Commun. Mass Spectrom. 24(17):2620-2624(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lee, P.S., et al. Blood Purif. 29(2):99-101(2010)
Solomon, J.P., et al. Biochemistry 48(48):11370-11380(2009)
Litwin, M., et al. Acta Biochim. Pol. 56(4):739-743(2009)

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$ 295.00
Cat# AM1936a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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