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AGTR1 Antibody (Center)

Mouse Monoclonal Antibody (Mab)

  • WB - AGTR1 Antibody (Center) AM1963B
    AGTR1 Antibody (Center) (Cat. #AM1963b) western blot analysis in Hela cell line lysates (35μg/lane).This demonstrates the AGTR1 antibody detected the AGTR1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30556
Other Accession P34976, P30555, NP_114038.1, NP_114438.1
Reactivity Human
Predicted Rabbit, Pig
Host Mouse
Clonality Monoclonal
Isotype IgM,k
Clone Names 338CT11.2.5
Calculated MW 41061 Da
Antigen Region 211-240 aa
Additional Information
Gene ID 185
Other Names Type-1 angiotensin II receptor, AT1AR, AT1BR, Angiotensin II type-1 receptor, AT1, AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B
Target/Specificity This AGTR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human AGTR1.
Dilution WB~~1:100~250
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAGTR1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGTR1
Synonyms AGTR1A, AGTR1B, AT2R1, AT2R1B
Function Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Liver, lung, adrenal and adrenocortical adenomas
Research Areas
Citations (0)

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Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].


Xu, M., et al. Atherosclerosis 213(1):191-199(2010)
Niu, W., et al. Hypertens. Res. 33(11):1137-1143(2010)
Procopciuc, L.M., et al. Eur. J. Intern. Med. 21(5):414-418(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Schuur, M., et al. J. Neurol. Neurosurg. Psychiatr. (2010) In press :

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Cat# AM1963B
(40 western blots)
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