|Application ||WB, E|
|Other Accession||NP_001761.3, NP_001171569.1|
|Calculated MW||61128 Da|
|Antigen Region||505-532 aa|
|Other Names||B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19, CD19|
|Target/Specificity||This CD19 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 505-532 amino acids from the C-terminal region of human CD19.|
|Format||Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CD19 Antibody (C-term) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Walter, K., et al. Oncogene 29(20):2927-2937(2010)
van Zelm, M.C., et al. J. Clin. Invest. 120(4):1265-1274(2010)
Mizuochi, T., et al. J. Interferon Cytokine Res. 30(4):243-252(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
El-Sayed, Z.A., et al. Egypt J Immunol 16(1):27-38(2009)
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