|Application ||WB, E|
|Other Accession||NP_001761.3, NP_001171569.1|
|Calculated MW||61128 Da|
|Antigen Region||505-532 aa|
|Other Names||B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19, CD19|
|Target/Specificity||This CD19 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 505-532 amino acids from the C-terminal region of human CD19.|
|Format||Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CD19 Antibody (C-term) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Walter, K., et al. Oncogene 29(20):2927-2937(2010)
van Zelm, M.C., et al. J. Clin. Invest. 120(4):1265-1274(2010)
Mizuochi, T., et al. J. Interferon Cytokine Res. 30(4):243-252(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
El-Sayed, Z.A., et al. Egypt J Immunol 16(1):27-38(2009)
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