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KCNJ3 Antibody (C-term)(Ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - KCNJ3 Antibody (C-term)(Ascites) AM1995a
    KCNJ3 Antibody (C-term) (Cat. #AM1995a) western blot analysis in HL-60 cell line lysates (35μg/lane).This demonstrates the KCNJ3 antibody detected the KCNJ3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P48549
Other Accession P63251, P63250, E1BNE9, NP_002230.1
Reactivity Human
Predicted Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 383CT22.2.1
Calculated MW 56603 Da
Antigen Region 390-418 aa
Additional Information
Gene ID 3760
Other Names G protein-activated inward rectifier potassium channel 1, GIRK-1, Inward rectifier K(+) channel Kir31, Potassium channel, inwardly rectifying subfamily J member 3, KCNJ3, GIRK1
Target/Specificity This KCNJ3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human KCNJ3.
Dilution WB~~1:1000~8000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCNJ3 Antibody (C-term)(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNJ3
Synonyms GIRK1
Function This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.


Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Wagner, V., et al. J. Cell. Biochem. 110(3):598-608(2010)
Holmegard, H.N., et al. Cardiology 115(3):176-181(2010)
Rusinova, R., et al. Pflugers Arch. 458(2):303-314(2009)
Robitaille, M., et al. Cell. Signal. 21(4):488-501(2009)

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$ 295.00
Cat# AM1995a
(40 western blots)
Availability: In Stock
Bulk Size
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