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CD68 Antibody(Ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - CD68 Antibody(Ascites) AM1996a
    CD68 Antibody (Cat. #AM1996a) western blot analysis in WiDr cell line lysates (35μg/lane).This demonstrates the CD68/CD68 (kpi) antibody detected the CD68/CD68 (kpi) protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P34810
Other Accession NP_001242.2, NP_001035148.1
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 404CT9.2.5
Calculated MW 37408 Da
Antigen Region 133-160 aa
Additional Information
Gene ID 968
Other Names Macrosialin, Gp110, CD68, CD68
Target/Specificity This CD68 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from human CD68.
Dilution WB~~1:1000~4000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD68 Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD68
Function Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Cellular Location Isoform Short: Cell membrane; Single-pass type I membrane protein
Tissue Location Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites
Research Areas
Citations (0)

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This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.


Leonarduzzi, G., et al. Mol Nutr Food Res 54 SUPPL 1, S31-S41 (2010) :
Strojnik, T., et al. Anticancer Res. 29(8):3269-3279(2009)
Sayed, S., et al. Eur J Vasc Endovasc Surg 38(1):20-25(2009)
Suzuki, Y., et al. Int J Rheum Dis 12(1):7-13(2009)
Chen, W.S., et al. Scand. J. Rheumatol. 38(2):154-155(2009)

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$ 295.00
Cat# AM1996a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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