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NCOA4 Antibody(Ascites)

Mouse Monoclonal Antibody (Mab)

Country
United States
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Ordering Information
Catalog # SizeAvailability Price  
AM2019a 0.1 ml In Stock
$ 265.00email & fax$ 251.75online
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NCOA4 Antibody(Ascites) - Product info

ApplicationWB
  • Applications Legend:
  • WB=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • FC=Flow Cytometry
  • DB=Dot Blot
Primary AccessionQ13772
Other AccessionNP_001138734.1, NP_001138732.1
ReactivityHuman
IsotypeIgM
Clone Names439CT10.4.4
Calculated MW69726 Da

NCOA4 Antibody(Ascites) - Additional info

Gene ID 8031
Other Names
NCOA4; ARA70; ELE1; RFG; Nuclear receptor coactivator 4; Androgen receptor coactivator 70 kDa protein; Androgen receptor-associated protein of 70 kDa; Ret-activating protein ELE1
Target/Specificity
Purified His-tagged NCOA4 protein(Fragment) was used to produced this monoclonal antibody.
Dilution
WB~~1:500~3200
Format
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
NCOA4 Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.

NCOA4 Antibody(Ascites) - Protein Information

Name NCOA4
Synonyms ARA70, ELE1, RFG
Function
Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.
Tissue Location
Widely expressed. Also detected in adipose tissues and in different cell lines. Isoform Beta is only expressed in testis

NCOA4 Antibody(Ascites) - Related products

AM2019b: NCOA4 Antibody

AP16218b: NCOA4 Antibody (C-term)

BP16218b: NCOA4 Antibody (C-term) Blocking Peptide

AT2981a: NCOA4 Antibody (monoclonal) (M01)

AT2982a: NCOA4 Antibody (monoclonal) (M04)

AT2983a: NCOA4 Antibody (monoclonal) (M05)

NCOA4 Antibody(Ascites) - Research Areas

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BACKGROUND

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

REFERENCES

Sadow, P.M., et al. Endocr. Pathol. 21(2):73-79(2010)
Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) :
Richardson, D.S., et al. Cancer Res. 69(11):4861-4869(2009)
Peng, Y., et al. Am. J. Pathol. 172(1):225-235(2008)
Bongarzone, I., et al. Genomics 42(2):252-259(1997)