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GABARAP Antibody(Ascites)Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AM2025a | 0.1 ml 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
GABARAP Antibody(Ascites) - Product info | |
| Application | WB
|
| Primary Accession | O95166 |
| Other Accession | NP_009209.1 |
| Reactivity | Human, Mouse |
| Concentration | Crude ascites |
| Isotype | IgG1 |
| Clone Names | 424CT5.1.6 |
| Calculated MW | 13918 Da |
GABARAP Antibody(Ascites) - Additional info | |
| Gene ID 11337 | |
| Other Names GABARAP; FLC3B; Gamma-aminobutyric acid receptor-associated protein; GABA(A) receptor-associated protein; MM46 | |
| Target/Specificity Purified His-tagged GABARAP protein(Fragment) was used to produced this monoclonal antibody. | |
| Dilution WB~~1:500~2000 | |
| Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions GABARAP Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. | |
GABARAP Antibody(Ascites) - Protein Information | |
| Name GABARAP | |
| Synonyms FLC3B | |
| Function May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy (By similarity) | |
| Cellular Location Endomembrane system (By similarity). Cytoplasm, cytoskeleton (By similarity). Golgi apparatus membrane (By similarity). Cytoplasmic vesicle, autophagosome. Note=Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (By similarity) | |
| Tissue Location Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas | |
GABARAP Antibody(Ascites) - Related products
AM2025a: GABARAP Antibody(Ascites)
AP1821a: GABARAP Antibody (N-term)
AP1821b: GABARAP Antibody (Y95)
RI12109: GABARAP predesign siRNA
GABARAP Antibody(Ascites) - Application data
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GABARAP Antibody (Cat. #AM2025a) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the GABARAP antibody detected the GABARAP protein (arrow).
GABARAP Antibody(Ascites) - Research Areas
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BACKGROUND
Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
REFERENCES
Garcia-Martin, E., et al. J. Neurol. (2010) In press : Komoike, Y., et al. J. Hum. Genet. 55(3):155-162(2010) Thielmann, Y., et al. Proteins 77(3):637-646(2009) Schwarten, M., et al. Autophagy 5(5):690-698(2009) Kirkin, V., et al. Mol. Cell 33(4):505-516(2009)
