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B3GAT1 Antibody

Mouse Monoclonal Antibody (Mab)

  • WB - B3GAT1 Antibody AM2042a
    B3GAT1 Antibody (Cat. #AM2042a) western blot analysis in 293 cell line lysates (35μg/lane).This demonstrates the B3GAT1 antibody detected the B3GAT1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P2W7
Other Accession O35789, Q9CW73, NP_061114.2
Reactivity Human
Predicted Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 461CT17.4.1
Calculated MW 38256 Da
Antigen Region 132-160 aa
Additional Information
Gene ID 27087
Other Names Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Beta-1, 3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1, 3-glucuronyltransferase, GlcUAT-P, B3GAT1, GLCATP
Target/Specificity This B3GAT1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from human B3GAT1.
Dilution WB~~1:100~250
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsB3GAT1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name B3GAT1
Synonyms GLCATP
Function Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein
Tissue Location Mainly expressed in the brain.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized.


Akagi, J., et al. Int. J. Clin. Oncol. 15(2):145-152(2010)
Petrovas, C., et al. J. Immunol. 183(2):1120-1132(2009)
Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
Chong, L.K., et al. Eur. J. Immunol. 38(4):995-1000(2008)
Casado, J.G., et al. Tumour Biol. 29(5):304-310(2008)

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Cat# AM2042a
(40 western blots)
Availability: Inquire
Bulk Size
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