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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IL10 Antibody(Ascites)   

IL10 Antibody(Ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - IL10 Antibody(Ascites) AM2094a
    IL10 Antibody (Cat. #AM2094a) western blot analysis in MDA-MB231 cell line lysates (35μg/lane).This demonstrates the IL10 antibody detected the IL10 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22301
Other Accession P79338, P03180, NP_000563.1
Reactivity Human
Predicted EBV, Monkey
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 530CT10.5.7
Calculated MW 20517 Da
Antigen Region 27-53 aa
Additional Information
Gene ID 3586
Other Names Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF, IL10
Target/Specificity This IL10 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 27-53 amino acids from human IL10.
Dilution WB~~1:100~400
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL10 Antibody(Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL10
Function Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
Cellular Location Secreted.
Tissue Location Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types
Research Areas
Citations (0)

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The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq].


Huebinger, R.M., et al. J. Surg. Res. 164 (1), E141-E145 (2010) :
Glocker, E.O., et al. Lancet 376 (9748), 1272 (2010) :
Mosaad, Y.M., et al. Scand. J. Immunol. 72(4):358-364(2010)
Kung, W.J., et al. Diabetes Technol. Ther. 12(10):809-813(2010)
Santhosh, S., et al. Trop Gastroenterol 31(1):30-33(2010)

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$ 295.00
Cat# AM2094a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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