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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   MART-1/Melan-A Antibody (C-term) (Ascites)   

MART-1/Melan-A Antibody (C-term) (Ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - MART-1/Melan-A Antibody (C-term) (Ascites) AM2133a
    MART-1/Melan-A Antibody (C-term)(Ascites)(Cat. #AM2133a) western blot analysis in A2058 cell line lysates (35μg/lane).This demonstrates the MART-1/Melan-A antibody detected the MART-1/Melan-A protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16655
Other Accession NP_005502
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 610CT14.6.4
Calculated MW 13157 Da
Antigen Region 60-92 aa
Additional Information
Gene ID 2315
Other Names Melanoma antigen recognized by T-cells 1, MART-1, Antigen LB39-AA, Antigen SK29-AA, Protein Melan-A, MLANA, MART1
Target/Specificity This MART-1/Melan-A antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 60-92 amino acids from the C-terminal region of human MART-1/Melan-A.
Dilution WB~~1:100~1600
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMART-1/Melan-A Antibody (C-term) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MART1
Function Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Cellular Location Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation
Tissue Location Expression is restricted to melanoma and melanocyte cell lines and retina
Research Areas
Citations (0)

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MLANA is involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein SILV/PMEL17, which is critical to the formation of stage II melanosomes.


Li, Y., et al. J. Mol. Biol. 399(4):596-603(2010)
Giordano, F., et al. Hum. Mol. Genet. 18(23):4530-4545(2009)
Fernandez, L.P., et al. Exp. Dermatol. 18(7):634-642(2009)
Beltraminelli, H., et al. Am J Dermatopathol 31(3):305-308(2009)
Serana, F., et al. J Transl Med 7, 21 (2009) :

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$ 295.00
Cat# AM2133a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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