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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CYK18 Antibody (C-term) (Ascites)   

CYK18 Antibody (C-term) (Ascites)

Mouse Monoclonal Antibody (Mab)

  • WB - CYK18 Antibody (C-term) (Ascites) AM2178a
    CYK18 Antibody (C-term)(Ascites)(Cat. #AM2178a) western blot analysis in K562 cell line lysates (35μg/lane).This demonstrates the CYK18 antibody detected the CYK18 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05783
Other Accession NP_000215
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG3
Clone Names 695CT17.2.6
Calculated MW 48058 Da
Antigen Region 401-430 aa
Additional Information
Gene ID 3875
Other Names Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
Target/Specificity This CYK18 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the C-terminal region of human CYK18.
Dilution WB~~1:1000~8000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCYK18 Antibody (C-term) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT18
Synonyms CYK18
Function Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Cellular Location Cytoplasm, perinuclear region. Nucleus, nucleolus
Tissue Location Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Research Areas
Citations (0)

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KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.


Srikanth, B., et al. J. Biol. Chem. 285(44):34062-34071(2010)
Strnad, P., et al. Gastroenterology 139(3):828-835(2010)
Yamashiro, Y., et al. Biochem. Biophys. Res. Commun. 399(3):365-372(2010)
Nagashio, R., et al. Pathol. Int. 60(2):71-77(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

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$ 295.00
Cat# AM2178a
(40 western blots)
Availability: In Stock
Bulk Size
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