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CDX1 Antibody (C-term)

Mouse Monoclonal Antibody (Mab)

     
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  • WB - CDX1 Antibody (C-term) AM2194b
    All lanes : Anti-CDX1 (C-term) at 1:1000-1:2000 dilution Lane 1: mouse liver lysate Lane 2: mouse testis lysate Lane 3: human testis lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • WB - CDX1 Antibody (C-term) AM2194b
    All lanes : Anti-CDX1 Antibody (C-term) at 1:1000-1:2000 dilution Lane 1: mouse liver lysate Lane 2: mouse testis lysate Lane 3: WiDr whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • WB - CDX1 Antibody (C-term) AM2194b
    CDX1 Antibody (C-term) (Cat. #AM2194b) western blot analysis in WiDr,Hela cell line and mouse liver tissue lysates (35μg/lane).This demonstrates the CDX1 antibody detected the CDX1 protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P47902
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone/Animal Names 937CT11.6.2
Calculated MW 28138 Da
Additional Information
Gene ID 1044
Other Names Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1
Target/Specificity Purified His-tagged CDX1 protein was used to produced this monoclonal antibody.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDX1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDX1
Function Plays a role in transcriptional regulation (PubMed:24623306). Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536).
Cellular Location Nucleus.
Tissue Location Intestinal epithelium.
Research Areas
Citations (0)
citation

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Background

Could play a role in the terminal differentiation of the intestine.

References

Bonner C.A., et al. Genomics 28:206-211(1995).
Mallo G.V., et al. Int. J. Cancer 74:35-44(1997).
Malakooti J., et al. Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.

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$ 365.00
$ 140.00
Cat# AM2194b
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