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ACE2 Antibody

Mouse Monoclonal Antibody (Mab)

     
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  • WB - ACE2 Antibody AM2197b
    ACE2 (SARS Receptor) Antibody (Center) (Cat. #AM2197b) western blot analysis in 293,K562,MCF-7,SK-BR-3,T47D,MDA-MB-453 cell line and mouse testis tissue lysates (35μg/lane).This demonstrates the ACE2 antibody detected the ACE2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9BYF1
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgM,k
Clone Names 881CT16.4.4
Calculated MW 92463 Da
Additional Information
Gene ID 59272
Other Names Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog, ACEH, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2, ACE2
Target/Specificity Purified His-tagged ACE2 protein was used to produced this monoclonal antibody.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsACE2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACE2
Function Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
Cellular Location Processed angiotensin-converting enzyme 2: Secreted
Tissue Location Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level) Expressed in heart, kidney, testis, and gastrointestinal system
Research Areas
Citations (0)

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Background

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

References

Donoghue M., et al. Circ. Res. 87:E1-E9(2000).
Tipnis S.R., et al. J. Biol. Chem. 275:33238-33243(2000).
Douglas G.C., et al. Endocrinology 145:4703-4711(2004).
Itoyama S., et al. Am. J. Med. Genet. A 136:52-57(2005).
Suzuki Y., et al. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
$ 99.00
Cat# AM2197b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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