|Application ||IHC-P, WB, E|
|Calculated MW||53365 Da|
|Other Names||M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C|
|Target/Specificity||This MPIP3 antibody is generated from a mouse immunized with a recombinant protein.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MPIP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.|
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Provided below are standard protocols that you may find useful for product applications.
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
Sadhu K.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:5139-5143(1990).
Bureik M.,et al.Int. J. Oncol. 17:1251-1258(2000).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Wegener S.,et al.Eur. J. Cell Biol. 79:810-815(2000).
Hernandez S.,et al.Lab. Invest. 81:465-473(2001).
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