|Application ||IF, FC, WB, E|
|Calculated MW||35057 Da|
|Other Names||N-myc-interactor, Nmi, N-myc and STAT interactor, NMI|
|Target/Specificity||This NMI antibody is generated from a mouse immunized with a recombinant protein of human NMI.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NMI Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5.|
|Tissue Location||Expressed in all adult and fetal tissues except brain and skin. More abundant in fetal tissues especially liver|
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May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5.
Bao J.,et al.Oncogene 12:2171-2176(1996).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Zhu M.-H.,et al.Cell 96:121-130(1999).
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