|Application ||FC, WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||22977 Da|
|Other Names||Ras-related protein Rab-18, RAB18|
|Target/Specificity||This RAB18 antibody is generated from a mouse immunized with a recombinant protein of human RAB18.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB18 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
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Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.
Chikri M.M.,et al.Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
Schaefer U.,et al.FEBS Lett. 466:148-154(2000).
Dou T.,et al.DNA Seq. 16:230-234(2005).
Cui W.C.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
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