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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RRAS2 Antibody   

RRAS2 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
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  • WB - RRAS2 Antibody AM8512b
    All lanes : Anti-RRAS2 Antibody at 1:4000 dilution Lane 1: A431 whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 23 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P62070
Other Accession P62071
Reactivity Human, Mouse
Predicted Mouse
Host Mouse
Clonality monoclonal
Isotype IgG1,k
Clone Names 1578CT130.349.47.14
Calculated MW 23400 Da
Additional Information
Gene ID 22800
Other Names Ras-related protein R-Ras2, Ras-like protein TC21, Teratocarcinoma oncogene, RRAS2, TC21
Target/Specificity This RRAS2 antibody is generated from a mouse immunized with a recombinant protein of human RRAS2.
Dilution WB~~1:4000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRRAS2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RRAS2
Synonyms TC21
Function It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS)
Tissue Location Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.
Research Areas
Citations (0)

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Background

It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.

References

Drivas G.T.,et al.Mol. Cell. Biol. 10:1793-1798(1990).
Chan A.M.-L.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:7558-7562(1994).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).

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$ 295.00
$ 99.00
Cat# AM8512b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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