|Application ||WB, E|
|Calculated MW||506273 Da|
|Other Names||Protocadherin Fat 1, Cadherin family member 7, Cadherin-related tumor suppressor homolog, Protein fat homolog, Protocadherin Fat 1, nuclear form, FAT1, CDHF7, FAT|
|Target/Specificity||This FAT1 antibody is generated from a mouse immunized with a recombinant protein between 4203-4539 amino acids from human FAT1.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FAT1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Nucleus. Cytoplasm, perinuclear region|
|Tissue Location||Expressed in many epithelial and some endothelial and smooth muscle cells|
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Provided below are standard protocols that you may find useful for product applications.
Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact.
Dunne J.,et al.Genomics 30:207-223(1995).
Hillier L.W.,et al.Nature 434:724-731(2005).
Magg T.,et al.Exp. Cell Res. 307:100-108(2005).
Cantin G.T.,et al.J. Proteome Res. 7:1346-1351(2008).
Hou R.,et al.J. Biol. Chem. 284:6955-6965(2009).
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