|Application ||WB, E|
|Calculated MW||133470 Da|
|Other Names||Integrin alpha-11, ITGA11|
|Target/Specificity||This ITGA11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 675-880 amino acids from human ITGA11.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ITGA11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Integrin alpha-11/beta-1 is a receptor for collagen.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver|
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Provided below are standard protocols that you may find useful for product applications.
Integrin alpha-11/beta-1 is a receptor for collagen.
Lehnert K.,et al.Genomics 60:179-187(1999).
Velling T.,et al.J. Biol. Chem. 274:25735-25742(1999).
Zody M.C.,et al.Nature 440:671-675(2006).
Xu Y.Y.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Pellinen T.,et al.J. Cell Biol. 173:767-780(2006).
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