|Application ||WB, E|
|Calculated MW||32742 Da|
|Other Names||Glycine N-methyltransferase, 22.214.171.124, GNMT|
|Target/Specificity||This GNMT antibody is generated from a mouse immunized with a recombinant protein between 1-295 amino acids from the human GNMT.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNMT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.|
|Tissue Location||Abundant in liver.|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Chen Y.-M.A.,et al.Int. J. Cancer 75:787-793(1998).
Chen Y.-M.A.,et al.Genomics 66:43-47(2000).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ogawa H.,et al.Comp. Biochem. Physiol. 106B:601-611(1993).
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