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Retinoic Acid Receptor, α-Isotype Antibody

Affinity purified mouse monoclonal antibody

  • WB - Retinoic Acid Receptor, α-Isotype Antibody AN1098
    Western blot of rat hippocampal lysate showing specific immunolabeling of the ~48k RAR-α protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10276
Reactivity Human, Rat
Predicted Bovine, Mouse, Pig
Host Mouse
Clonality monoclonal
Isotype IgG1
Clone Names 763
Calculated MW 48 KDa
Additional Information
Gene ID 5914
Gene Name RARA
Other Names Retinoic acid receptor alpha, RAR-alpha, Nuclear receptor subfamily 1 group B member 1, RARA, NR1B1
Target/Specificity Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.
Dilution WB~~ 1:1000
Format Prepared from mouse ascites by ammonium sulfate precipitation followed affinity purification on a Protein G column.
Antibody Specificity Specific for the ~48k RAR-α isotype.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRetinoic Acid Receptor, α-Isotype Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
ShippingBlue Ice
Research Areas
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Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).


Abu J, Batuwangala M, Herbert K, Symonds P (2005) Retinoic acid and retinoid receptors: potential chemopreventive and therapeutic role in cervical cancer. Lancet Oncol 6:712-720.
Joshi S, Guleria R, Pan J, Dipette D, Singh US (2005) Retinoic acid receptors and tissue-trans-glutaminase mediate short-term effect of retinoic acid on migration and invasion of neuroblastoma SH-SY5Y cells. Oncogene advance online publication 12 September 2005; doi: 10.1038/sj.onc.1209027.
Lane MA, Bailey SJ (2005) Role of retinoid signalling in the adult brain. Prog Neurobiol 75:275-293.

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$ 335.00
Cat# AN1098
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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