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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Phospho Antibodies   >   Thyroid Hormone Receptor, β-Isotype Antibody   

Thyroid Hormone Receptor, β-Isotype Antibody

Affinity purified mouse monoclonal antibody.

  • WB - Thyroid Hormone Receptor, β-Isotype Antibody AN1103
    Western blot of hippocampal lysate showing specific immunolabeling of the ~58k TR-β protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10828
Reactivity Human
Host Mouse
Clonality monoclonal
Isotype IgG1
Clone Names 2386
Calculated MW 55 KDa
Additional Information
Gene ID 7068
Gene Name THRB
Other Names Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta, THRB, ERBA2, NR1A2, THR1
Target/Specificity Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.
Dilution WB~~ 1:1000
Format Prepared from mouse ascites by ammonium sulfate precipitation followed by affinity purification on a protein G column.
Antibody Specificity Specific for the ~55k TR-β protein.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsThyroid Hormone Receptor, β-Isotype Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
ShippingBlue Ice
Research Areas
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Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory (Ambrogini et al., 2005; Chan and Kilby, 2000). Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain (Constantinou et al., 2005).


Ambrogini P, Cuppini R, Ferri P, Mancini C, Ciaroni S, Voci A, Gerdoni E, Gallo G (2005) Thyroid hormones affect
neurogenesis in the dentate gyrus of adult rat. Neuroendocrinology 81:244-253.
Chan S, Kilby MD (2000) Thyroid hormone and central nervous system development. J Endocrinol 165:1-8.
Constantinou C, Margarity M, Valcana T (2005) Region-specific effects of hypothyroidism on the relative expression
of thyroid hormone receptors in adult rat brain. Mol Cell Biochem 278:93-100.

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$ 335.00
Cat# AN1103
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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