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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Phospho Antibodies   >   Ribosomal S6 Kinase 2 Antibody   

Ribosomal S6 Kinase 2 Antibody

Affinity purified rabbit polyclonal antibody

  • WB - Ribosomal S6 Kinase 2  Antibody AN1106
    Western blot of HeLa lysate showing specific immunolabeling of the ~90k RSK2 protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9WUT3
Reactivity Human
Predicted Bovine, Chicken, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 90 KDa
Additional Information
Gene ID 20112
Gene Name RPS6KA2
Other Names Ribosomal protein S6 kinase alpha-2, S6K-alpha-2, 90 kDa ribosomal protein S6 kinase 2, p90-RSK 2, p90RSK2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, Protein-tyrosine kinase Mpk-9, Ribosomal S6 kinase 3, RSK-3, pp90RSK3, Rps6ka2, Mapkapk1c, Rsk3
Target/Specificity Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Dilution WB~~ 1:1000
Format Prepared from rabbit serum by affinity purification via chromatography on an affinity column made with the C-terminal peptide used as antigen.
Antibody Specificity Specific for ~90k RSK2 protein.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRibosomal S6 Kinase 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
ShippingBlue Ice
Research Areas
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The p90 ribosomal S6 kinases (RSK)1–4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade . The loss of RSK2 activity in humans leads to Coffin–Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006).


Hanauer A, Young ID (2002) Coffin-Lowry syndrome:
clinical and molecular features. J Med Genet
Sheffler DJ, Kroeze WK, Garcia BG, Deutch AY, Hu
feisen SJ, Leahy P, Bruning
JC, Roth BL (2006) p90
ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling. Proc Natl Acad Sci
(USA) 103:4717-4722.

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$ 335.00
Cat# AN1106
(40 western blots)
Availability: 7-10 days
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