|Calculated MW||60 KDa|
|Target/Specificity||Human cell homogenate.|
|Format||Total IgG fraction|
|Antibody Specificity||Specific for human mitochondria in all cell types. The antibody works on acetone fixed and 2% paraformaldehyde fixed cells. The antibody also works for immunohistochemistry on 2% paraformaldehyde fixed (5-10 minutes) cryostat sections.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mitochondria Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Mitochondria are most commonly known as the power plants of the cell as they produce ATP, but they are also involved in many other important cellular processes such as cell signaling, growth and differentiation (McBride et al., 2006). In addition, mitochondria have been shown to play a role in apoptosis (Green 1998). This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.
McBride HM, Neuspiel M, Wasiak S (2006) Mitochondria: More than just a powerhouse. Curr
Green DR (1998) Apoptotic pathways: the roads to ruin. Cell 94(6):695-8.
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