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Olig2 Antibody

Rabbit polyclonal antibody

  • WB - Olig2 Antibody AN1177
    Western blot of neonatal rat brain lysate showing specific immunolabeling ofthe ~ 32k Olig2 protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9EQW6
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 27 KDa
Additional Information
Gene ID 50913
Gene Name OLIG2
Other Names Oligodendrocyte transcription factor 2, Oligo2, Olig2
Target/Specificity Recombinant mouse Olig2.
Dilution WB~~ 1:3000
Format Protein A purified rabbit serum.
Antibody Specificity Specific for the ~32 kDa Olig2 protein in Western blots. The antibody also works well for immunohistochemistry and immunocytochemistry.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOlig2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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Research Areas
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Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007).


Arnett, H.A., et al. (2004) bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS. Science 306(5704):2111-5.
Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, Depinho RA, Anderson DJ, Stiles CD, Rowitch DH (2007) Olig2 regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron 53(4):503-17.

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$ 335.00
Cat# AN1177
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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