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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Phospho Antibodies   >   Adenylate Cyclase III Antibody   

Adenylate Cyclase III Antibody

Rabbit polyclonal antibody

  • WB - Adenylate Cyclase III Antibody AN1220
    Western blot of rat cortex lysate showing specific immunolabeling of the ~160k adenylate cyclase III protein.
  • IF - Adenylate Cyclase III Antibody AN1220
    Immunofluorescence of cultured rat neurons and glia showing strong staining of neuronal cilia using our anti-adenylate cyclase III antibody (red) and axonal and dendritic staining of alpha II spectrin (green) revealing the submembraneous cytoskeleton and DNA (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P21932
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Calculated MW 160, 200 KDa
Additional Information
Gene ID 64508
Gene Name ADCY3
Other Names Adenylate cyclase type 3, ATP pyrophosphate-lyase 3, Adenylate cyclase type III, AC-III, Adenylate cyclase, olfactive type, Adenylyl cyclase 3, AC3, Adcy3
Target/Specificity Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Dilution WB~~ 1:2000
IF~~ 1:500
Format Affinity purified rabbit serum.
Antibody Specificity Specific for the ~160 kDa adenylate cyclase III protein.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAdenylate Cyclase III Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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Adenylate cyclase is the enzyme which produces the “second messenger” signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004; Louvi and Grove 2011).


Fuchs JL, Schwark HD. (2004) Neuronal primary cilia: a review. Cell Biol Int. 28:111-8.
Louvi A and Grove EA. (2011) Cilia in the CNS: the quiet organelle claims center stage. Neuron 69:1046-1060

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$ 335.00
Cat# AN1220
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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