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FOX3 (NeuN) Antibody

Mouse monoclonal antibody

  • WB - FOX3 (NeuN) Antibody AN1241
    Western blot of rat cortex lysate showing specific immunolabeling of the ~46/48k FOX3 protein.
  • IF - FOX3 (NeuN) Antibody AN1241
    Immunofluorescence of cultured rat neurons showing strong nuclear and distal cytoplasmic staining of FOX3 in red and the complete absence of astrocyte staining, which are stained green using our GFAP antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession A6NFN3
Reactivity Bovine, Human, Mouse, Rat
Host Mouse
Clonality monoclonal
Isotype IgG2a
Clone Names 1B7
Calculated MW 46/48 KDa
Additional Information
Gene ID 146713
Gene Name RBFOX3
Other Names RNA binding protein fox-1 homolog 3, Fox-1 homolog C, RBFOX3
Target/Specificity Recombinant protein taken from the N-terminus of human FOX3 expressed in and purified from E. Coli.
Dilution WB~~ 1:2000
IF~~ 1:500
Format Affinity purified from tissue culture supernatant.
Antibody Specificity Specific for the ~46/48k FOX3 protein doublet.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFOX3 (NeuN) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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FOX3, also known as NeuN and hexaribonucleotide binding protein 3, is a neuron-specific RNA binding nuclear protein involved in the regulation of pre-mRNA alternative splicing (Kim et al., 2009). FOX3 dependent alternative splicing of Numb has recently been shown to play an important role in the progression of neuronal differentiation during vertebrate development (Kim et al., 2013).


Kim KK, Adelstein RS, Kawamoto S (2009) Identification of neuronal nuclei (NeuN) as Fox-3, a new
member of the Fox-1 gene family of splicing factors. J Biol Chem. Nov 6; 284(45):31052-61.
Kim KK, Nam J, Mukouyama YS, Kawamoto S. (2013) Rbfox3-regulated alternative splicing of Numb
promotes neuronal differentiation during development. J Cell Biol. Feb 18;200(4):443-58

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$ 335.00
Cat# AN1241
(40 western blots)
Availability: 7-10 days
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