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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IFN-gamma Antibody   

IFN-gamma Antibody

Purified Mouse Monoclonal Antibody

  • WB - IFN-gamma Antibody AO1009a
    Figure 1: Western blot analysis using IFN gamma mouse mAb against truncated IFN-gamma recombinant protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01579
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3F1E3
Isotype IgG1
Calculated MW 19.3kDa
Description Interferon-γ (IFN-γ) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-γ strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB
Immunogen Purified recombinant fragment of human IFN-γ expressed in E. Coli.
Formulation Purified antibody in PBS containing 0.03% sodium azide.
Additional Information
Gene ID 3458
Other Names Interferon gamma, IFN-gamma, Immune interferon, IFNG
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIFN-gamma Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Cellular Location Secreted.
Tissue Location Released primarily from activated T lymphocytes
Research Areas
Citations (0)

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1. Takayanagi, H. et al. Nature 2000. 408: 600-605. 2. Tsubota, K. et al. Invest. Ophthal. Vis. Sci. 40: 28-34, 1999.

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$ 300.00
Cat# AO1009a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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