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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IL-1a Antibody   

IL-1a Antibody

Purified Mouse Monoclonal Antibody

  • WB - IL-1a Antibody AO1010a
    Figure 1: Western blot analysis using IL1a mouse mAb against truncated IL1a recombinant protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01583
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3A6F11; 1F3B3
Isotype IgG2a
Calculated MW 30.6kDa
Description Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease
Immunogen Purified recombinant fragment of human IL1a expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 3552
Other Names Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, IL1A, IL1F1
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL-1a Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL1A
Synonyms IL1F1
Function Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Cellular Location Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins
Research Areas
Citations (0)

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1. Du,Y.; et al. 2000. Neurology 55: 480-484. 2. Grimaldi, L. et al. Ann. Neurol. 47: 361-365, 2000.

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$ 300.00
Cat# AO1010a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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