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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IL-6 Antibody   

IL-6 Antibody

Purified Mouse Monoclonal Antibody

  • WB - IL-6 Antibody AO1021a
    Figure 1: Western blot analysis using IL6 mouse mAb against IL6 recombinant protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05231
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6D9A1; 6C12B1
Isotype IgG1
Calculated MW 23718 Da
Description Interleukine 6 (IL-6) is a cytokine produced primarily by stimulated monocytes, fibroblasts and epithelial cells. It has a wide variety of biological functions through activating a cellsurface signaling assembly composed of IL6, IL6RA, and the shared signaling receptor gp130. The cytokine plays an essential role in the final differentiation of b-cells into Igsecreting cells, and induces myeloma, plasmacytoma growth, nerve cells differentiations. In addition, IL-6 is an important regulator of acute phase reaction.
Immunogen Purified recombinant fragment of human IL-6 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 3569
Other Names Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL-6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL6
Synonyms IFNB2
Function Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Cellular Location Secreted.
Research Areas
Citations (0)

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1. Ota, N. et al. 2001. J. Hum. Genet. 46: 267-272.

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$ 300.00
Cat# AO1021a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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