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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Trim5a Antibody   

Trim5a Antibody

Purified Mouse Monoclonal Antibody

  • WB - Trim5a Antibody AO1023a
    Figure 1: Western blot analysis using Trim5α mouse mAb against human breast carcinoma tissue lysate.
  • IHC - Trim5a Antibody AO1023a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human metastatic adenocarcinoma(A) and stomach adenocarcinoma (B), showing cytoplasmic localization using Trim5α mouse mAb with AEC staining (A) and DAB staining(B).
  • WB - Trim5a Antibody AO1023a
    Figure 3: Western blot analysis using Trim5α mouse monoclonal antiobdy against truncated Trim5αrecombinant protein.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NUD5
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3B11H2
Isotype IgG1
Calculated MW 43618 Da
Description TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.
Immunogen Purified recombinant fragment of human trim5 alpha expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 85364
Other Names Zinc finger CCHC domain-containing protein 3, ZCCHC3, C20orf99
Dilution WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTrim5a Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C20orf99
Research Areas
Citations (0)

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1. Stremlau, M. Nature 2004.427:848-53. 2. Song, B. J Virol. 2005.79(7):3930-7.

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$ 385.00
Cat# AO1023a
(40 western blots)
Availability: 7-10 days
Bulk Size
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