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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KSHV ORF26 Antibody   

KSHV ORF26 Antibody

Purified Mouse Monoclonal Antibody

  • WB - KSHV ORF26 Antibody AO1034a
    Figure 1: Western blot analysis using KSHV ORF26 mouse mAb against TPA induced BCBL-1 cell lysate.
  • IHC - KSHV ORF26 Antibody AO1034a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma (left) and kidney carcinoma (right), showing cytoplasmic localization using GAPDH mouse mAb with DAB staining.
  • IF - KSHV ORF26 Antibody AO1034a
    Figure 3: Confocal immunofluorescence analysis of methanol-fixed HepG2 (left) and Hela (right) cells using anti-GAPDH mAb (green), showing cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession F5HGN8
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2F6B8
Isotype IgG1
Calculated MW 34373 Da
Description Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF26 open reading frames are juxtaposed and span from nucleotide (nt) 46933 to 47850 of the virus genome. Akula et al (2003) report it acts as a Capsid protein.
Immunogen Purified recombinant fragment of KSHV ORF26 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 4961509
Other Names Triplex capsid protein VP23 homolog, ORF26
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKSHV ORF26 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ORF26
Function Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of the major capsid protein, which are linked together by heterotrimers called triplex. These triplex are formed by a single molecule of VP19C and two copies of VP23 which bridge major capsid protein multimers together. Triplexes occupy the local threeflod positions between capsid hexamers and pentamers. Additionally, VP19C is required for efficient transport of VP23 to the nucleus, which is the site of capsid assembly (By similarity).
Cellular Location Virion. Host nucleus
Research Areas
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1. James J . Proc. Natl. Acad. Sci Vol. 1996. 93, pp. 14862-14867.

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$ 300.00
Cat# AO1034a
(40 western blots)
Availability: 7-10 days
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