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S100A10/P11 Antibody

Purified Mouse Monoclonal Antibody

     
  • WB - S100A10/P11 Antibody AO1094a
    Figure 1: Western blot analysis using S100A10/P11 mouse mAb against MCF-7 (1), HepG2 (2) and Hela (3).
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  • IHC - S100A10/P11 Antibody AO1094a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human nerve and ganglion cells using S100A10/P11 mouse mAb.
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  • IF - S100A10/P11 Antibody AO1094a
    Figure 3: Confocal immunofluorescence analysis of Hela (left) and L-02 (right) cells using S100A10/P11 mouse mAb(green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, ICC, E
Primary Accession P60903
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4E7E10
Isotype IgG1
Calculated MW 11kDa
Description S100 calcium binding protein A10 (S100A10/P11), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis.
Immunogen Purified recombinant fragment of human P11 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 6281
Other Names Protein S100-A10, Calpactin I light chain, Calpactin-1 light chain, Cellular ligand of annexin II, S100 calcium-binding protein A10, p10 protein, p11, S100A10, ANX2LG, CAL1L, CLP11
Dilution WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsS100A10/P11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name S100A10
Synonyms ANX2LG, CAL1L, CLP11
Function Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.
Research Areas
Citations (0)
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References

1. Svenningsson P, Greengard P. Curr Opin Pharmacol. 2007;7(1):27-32. 2. Santamaria-Kisiel L, Rintala-Dempsey AC, Shaw GS. Biochem J. 2006;396(2):201-14. 3. Rust R, VL, van dJ, Harms G,.et al. Br J Haematol. 2005;131(5):596-608.

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$ 300.00
Cat# AO1094a
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