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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ALCAM Antibody   

ALCAM Antibody

Purified Mouse Monoclonal Antibody

  • WB - ALCAM Antibody AO1180a
    Figure 1: Western blot analysis using ALCAM mouse mAb against truncated Trx-ALCAM recombinant protein (1).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13740
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3F8B12
Isotype IgG2a
Calculated MW 65102 Da
Description ALCAM(CD166): Activated leukocyte cell adhesion molecule.CD166 is a member of the Ig superfamily and is expressed on activated T-cells, B cells and other cells including thymic epithelial cells, fibroblasts, keratinocytes and neurons. CD6 has been identified as a receptor for CD166.
Immunogen Purified recombinant fragment of ALCAM (aa405-524) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 214
Other Names CD166 antigen, Activated leukocyte cell adhesion molecule, CD166, ALCAM, MEMD
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsALCAM Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MEMD
Function Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines.
Research Areas
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1. Prostate. 2003 Jan 1;54(1):34-43. 2. J Clin Endocrinol Metab. 2003 Jul;88(7):3437-43. 3. J Cell Sci. 2004 Jun 1;117(Pt 13):2841-52.

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$ 300.00
Cat# AO1180a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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