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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   SND1/P100 Antibody   

SND1/P100 Antibody

Purified Mouse Monoclonal Antibody

     
  • WB - SND1/P100 Antibody AO1189a
    Figure 1: Western blot analysis using SND1/P100 mouse mAb against Hela (1), Jukat (2), HepG2 (3) SMMC-7721 (4) cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q7KZF4
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2D7
Isotype IgG1
Calculated MW 102kDa
Description SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
Immunogen Purified recombinant fragment of SND1 (aa361-485) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 27044
Other Names Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator, EBNA2 coactivator p100, Tudor domain-containing protein 11, p100 co-activator, SND1, TDRD11
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSND1/P100 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SND1
Synonyms TDRD11
Function Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).
Cellular Location Cytoplasm. Nucleus. Melanosome. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue Location Ubiquitously expressed.
Research Areas
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References

1. J Gen Virol. 2003 Sep;84(Pt 9):2317-22. 2. Biochim Biophys Acta. 2005 Jan 11;1681(2-3):126-33.

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$ 325.00
Cat# AO1189a
Size:
Quantity:
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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