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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ETV1 Antibody   

ETV1 Antibody

Purified Mouse Monoclonal Antibody

  • WB - ETV1 Antibody AO1230a
    Figure 1: Western blot analysis using ETV1 mouse mAb against truncated Trx-ETV1 recombinant protein (1) and full-length ETV1 (aa1-477)-hIgGFc transfected CHO-K1 cell lysate(2).
  • WB - ETV1 Antibody AO1230a
    Figure 2: Western blot analysis using ETV1 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ETV1 cDNA (2).
  • IHC - ETV1 Antibody AO1230a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human Thyroid tissues using LAMB1 mouse mAb
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50549
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1C8B6
Isotype IgG1
Calculated MW 55131 Da
Description ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.
Immunogen Purified recombinant fragment of ETV1 (aa1-191) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 2115
Other Names ETS translocation variant 1, Ets-related protein 81, ETV1, ER81
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsETV1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ETV1
Synonyms ER81
Function Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Cellular Location Nucleus.
Tissue Location Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes
Research Areas
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1. Neoplasia. 2006 Oct;8(10):826-32. 2. Cancer Genet Cytogenet. 2008 May;183(1):21-7.

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$ 325.00
Cat# AO1230a
(40 western blots)
Availability: 7-10 days
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