|Application ||WB, IHC, E|
|Calculated MW||44998 Da|
|Description||BHMT: betaine-homocysteine methyltransferase. This protein is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.|
|Immunogen||Purified recombinant fragment of BHMT expressed in E. Coli.|
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Other Names||Betaine--homocysteine S-methyltransferase 1, 188.8.131.52, BHMT|
|Dilution||WB~~1/500 - 1/2000|
IHC~~1/200 - 1/1000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BHMT Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.|
|Tissue Location||Found exclusively in liver and kidney.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Genome Res. 2004 Oct;14(10B):2121-7. 2. Biochem J. 2007 Jan 1;401(1):87-96.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.