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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   EphA6 Antibody   

EphA6 Antibody

Purified Mouse Monoclonal Antibody

  • WB - EphA6 Antibody AO1237a
    Figure 1: Western blot analysis using EphA6 mouse mAb against truncated MBP-EphA6 recombinant protein (1) and truncated GST-EphA6(aa695-795) recombinant protein (2).
  • IHC - EphA6 Antibody AO1237a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human Liver tissues using LPA mouse mAb
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UF33
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3D5B10
Isotype IgG1
Calculated MW 116379 Da
Description EphA6: EPH receptor A6. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1(Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12),EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3(Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. Ephrin-A2(ELF-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).
Immunogen Purified recombinant fragment of EphA6 (aa695-795) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 285220
Other Names Ephrin type-A receptor 6,, EPH homology kinase 2, EHK-2, EPH-like kinase 12, EK12, EPHA6, EHK2, HEK12
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEphA6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EPHA6
Synonyms EHK2, HEK12
Function Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in brain and testis.
Research Areas
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1. Curr Biol. 2004 Feb 3;14(3):R121-3. 2. Genome Res. 2006 Jan;16(1):55-65.

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$ 325.00
Cat# AO1237a
(40 western blots)
Availability: 7-10 days
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