|Application ||WB, IHC, E|
|Clone Names||8F6A9; 8H5C5|
|Description||LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation.|
|Immunogen||Purified recombinant fragment of LPA (4330-4521) expressed in E. Coli.|
|Formulation||Ascitic fluid containing 0.03% sodium azide. |
|Dilution||WB~~1/500 - 1/2000|
IHC~~1/200 - 1/1000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LPA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. J Stroke Cerebrovasc Dis. 2007 Sep-Oct;16(5):220-4. 2. Clin Chim Acta. 2008 Jan;387(1-2):109-12.
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