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Myostatin Antibody

Purified Mouse Monoclonal Antibody

     
  • WB - Myostatin Antibody AO1255a
    Figure 1: Western blot analysis using Myostatin mouse mAb against truncated Myostatin-His recombinant protein (1).
    detail
  • IHC - Myostatin Antibody AO1255a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human Testis tissues using ApoO mouse mAb
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O14793
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6H12
Isotype IgG1
Calculated MW 42.7kDa
Description The protein is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
Immunogen Purified recombinant fragment of Myostatin expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 2660
Other Names Growth/differentiation factor 8, GDF-8, Myostatin, MSTN, GDF8
Dilution WB~~1/500 - 1/2000
IHC~~1:200~~1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMyostatin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSTN
Synonyms GDF8
Function Acts specifically as a negative regulator of skeletal muscle growth.
Cellular Location Secreted {ECO:0000250|UniProtKB:O08689}.
Research Areas
Citations (0)
citation

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References

1. Clin Chim Acta. 2008 May;391(1-2):115-7. 2. Folia Morphol (Warsz). 2008 Feb;67(1):6-12.

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$ 300.00
Cat# AO1255a
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