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Cytokeratin 5 AntibodyMouse Monoclonal Antibody to Cytokeratin 5
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AO1256a | 0.1ml 400 ul | 7-10 days | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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- Backgrounds
Cytokeratin 5 Antibody - Product info | |
| Application | WB
|
| Primary Accession | P13647 |
| Other Accession | NP_000415.2 |
| Reactivity | Human |
| Isotype | Mouse IgG1 |
| Clone Names | 10 |
| Calculated MW | 62378 Da |
Cytokeratin 5 Antibody - Additional info | |
| Gene ID 3852 | |
| Other Names K5; CK5; KRT5A; KRT5 | |
| Target/Specificity Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli. | |
| Dilution WB~~1:500 - 2000. | |
| Format Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Cytokeratin 5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Cytokeratin 5 Antibody - Protein Information | |
| Name KRT5 | |
Cytokeratin 5 Antibody - Application data
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Figure 1: Western blot analysis using anti-CK5 monoclonal antibody against Hela cell lysate(1).
Cytokeratin 5 Antibody - Related products
AT2660a: KRT5 Antibody (monoclonal) (M08)
AO1114a: Cytokeratin 5 Antibody
AO1115a: Cytokeratin (Pan) Antibody
AO1256a: Cytokeratin 5 Antibody
AO1269a: Cytokeratin(Pan) Antibody
AJ1227a: Cytokeratin-5 Antibody
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.
REFERENCES
1. J Invest Dermatol. 2003 Sep;121(3):482-5.
2. J Cell Sci. 2005 Mar 1;118(Pt 5):1081-90.
