CD37 Antibody
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| ICC, E |
---|---|
Primary Accession | P11049 |
Reactivity | Human, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2B8 |
Isotype | IgG1 |
Calculated MW | 31.7kDa |
Description | CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | Purified recombinant fragment of CD37 expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Gene ID | 951 |
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Other Names | Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37, CD37, TSPAN26 |
Dilution | IF~~1/200 - 1/1000 WB~~1:500~~2000 IHC~~1:200~~1000 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CD37 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD37 |
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Synonyms | TSPAN26 |
Cellular Location | Membrane; Multi-pass membrane protein. |
Tissue Location | B-lymphocytes. |
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Provided below are standard protocols that you may find useful for product applications.
References
1. J Immunol. 2004 Mar 1;172(5):2953-61. 2. J Immunol. 2007 Jan 1;178(1):154-62.
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