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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Cytokeratin 5 Antibody   

Cytokeratin 5 Antibody

Purified Mouse Monoclonal Antibody

  • WB - Cytokeratin 5 Antibody AO1263a
    Figure 1: Western blot analysis using CK5
    mouse mAb against Hela cell lysate (1).
  • IHC - Cytokeratin 5 Antibody AO1263a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human Prostate tissues using LCN1 mouse mAb
  • IF - Cytokeratin 5 Antibody AO1263a
    Figure 2: Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with LCN1-hIgGFc using anti-LCN1 monoclonal antioby(green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13647
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1E1
Isotype IgG1
Calculated MW 62.3kDa
Description Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.
Immunogen Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 3852
Other Names Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, CK-5, Keratin-5, K5, Type-II keratin Kb5, KRT5
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCytokeratin 5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT5
Research Areas
Citations (0)

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1. J Invest Dermatol. 2003 Sep;121(3):482-5. 2. J Cell Sci. 2005 Mar 1;118(Pt 5):1081-90.

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$ 325.00
Cat# AO1263a
(40 western blots)
Availability: 7-10 days
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