|Application ||WB, IHC, ICC, E|
|Description||LCN1: lipocalin 1 (tear prealbumin), also known as TP, PMFA, VEGP. Entrez Protein: NP_002288. The protein belongs to the lipocalin family. Lipocalins are a group of extracellular proteins that are able to bind lipophiles by enclosure within their structures to minimize solvent contact. This protein may bind hydrophobic ligands and inhibit cysteine proteinases. It may also play a role in taste reception and could be necessary for the concentration and delivery of sapid molecules in the gustatory system.|
|Immunogen||Purified recombinant fragment of LCN1 expressed in E. Coli. |
|Formulation||Ascitic fluid containing 0.03% sodium azide. |
|Other Names||Lipocalin-1, Tear lipocalin, Tlc, Tear prealbumin, TP, Von Ebner gland protein, VEG protein, LCN1, VEGP|
|Dilution||WB~~1/500 - 1/2000|
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LCN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.|
|Tissue Location||Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate|
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Provided below are standard protocols that you may find useful for product applications.
1. Adv Exp Med Biol. 2002;506(Pt A):555-65. 2. J Autoimmun. 2005 Nov;25(3):229-34.
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