Mouse Monoclonal Antibody to SOD1
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|AO1280a||100 µl||7-10 days||$ 325.00||Add to cart|
- Citations : 0
SOD1 Antibody - Product Information
|Application ||WB, FC, ICC, IF|
|Calculated MW||15936 Da|
SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene.
Purified recombinant fragment of human SOD1 expressed in E. Coli.
SOD1 Antibody - Additional Information
|Gene ID 6647|
Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, hSod1, SOD1
Ascitic fluid containing 0.03% sodium azide.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
SOD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
SOD1 Antibody - Protein Information
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria
SOD1 Antibody - Related Products
SOD1 Antibody - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
1. Apoptosis. 2005 May;10(3):499-502.
2. Hum Mol Genet. 2008 Nov 1;17(21):3303-17.