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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TBX5 Antibody   

TBX5 Antibody

Purified Mouse Monoclonal Antibody

  • WB - TBX5 Antibody AO1295a
    Figure 1: Western blot analysis using TBX5 mouse mAb against HepG2 cell lysate (1).
  • ICC - TBX5 Antibody AO1295a
    Figure 2: Confocal immunofluorescence analysis of HEK293 cells trasfected with extracellular ERBB3 (aa22-369)-hIgGFc using ERBB3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
  • IF - TBX5 Antibody AO1295a
    Figure 2: Confocal immunofluorescence analysis of HEK293 cells trasfected with extracellular ERBB3 (aa22-369)-hIgGFc using anti-ERBB3 monoclonal antioby (green). Blue: DRAQ5 fluorescent DNA dye.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99593
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 7B11
Isotype IgG1
Calculated MW 53kDa
Description TBX5, also known as T-box 5. It is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The TBX5 protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.
Immunogen Purified recombinant fragment of TBX5 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 6910
Other Names T-box transcription factor TBX5, T-box protein 5, TBX5
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBX5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBX5
Function Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}
Research Areas
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1. Physiol Genomics. 2004 Jul 8;18(2):129-40. 2. J Mol Cell Cardiol. 2003 Oct;35(10):1191-5.

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$ 325.00
Cat# AO1295a
(40 western blots)
Availability: 7-10 days
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