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AGT Antibody

Purified Mouse Monoclonal Antibody

  • WB - AGT Antibody AO1300a
    Figure 1: Western blot analysis using AGT mouse mAb against human plasma (1).
  • FC - AGT Antibody AO1300a
    Figure 3: Flow cytometric analysis of A549 cells using TUBB3 mouse mAb (green) and negative control (purple).
  • ICC - AGT Antibody AO1300a
    Figure 2: Immunofluorescence analysis of PANC-1 cells using TUBB3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • IF - AGT Antibody AO1300a
    Figure 2: Immunofluorescence analysis of PANC-1 cells using TUBB3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01019
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1B1
Isotype IgG2b
Calculated MW 53kDa
Description AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Immunogen Purified recombinant fragment of human AGT expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 183
Other Names Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin 1-10, Angiotensin I, Ang I, Angiotensin-2, Angiotensin 1-8, Angiotensin II, Ang II, Angiotensin-3, Angiotensin 2-8, Angiotensin III, Ang III, Des-Asp[1]-angiotensin II, Angiotensin-4, Angiotensin 3-8, Angiotensin IV, Ang IV, Angiotensin 1-9, Angiotensin 1-7, Angiotensin 1-5, Angiotensin 1-4, AGT, SERPINA8
Dilution WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAGT Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AGT
Synonyms SERPINA8
Function Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-3: stimulates aldosterone release.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)

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1. Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1900-7. 2. Regul Pept. 2006 Jan 15;133(1-3):155-9.

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$ 325.00
Cat# AO1300a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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